How to manage cuff pressure in children intubated with cuffed tubes
The choice of tube size for uncuffed tubes is commonly made according to Cole`s formula (Age/4 + 4 mm); for cuffed tubes a size 0.5 mm smaller is recommended. The cuff pressure needs to be sufficient to avoid leakage during mechanical ventilation, and also to completely seal the airway and prevent micro‑aspiration (thus preventing ventilator‑associated pneumonia).